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Notably, research indicates that individuals most interested in trying GLP-1 medications, and willing to accept common side effects, are those who report greater body shame, body surveillance, weight concerns, anti-fat bias, disordered eating behaviors, and higher BMIs, alongside lower body appreciation and body neutrality (Markey et al., 2025)

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Jadoon KA, Ratcliffe SH, Barrett DA, et al

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Retatrutide remains more research-focused in the published evidence base

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With the nations highest diabetes rate (18.2%) and over 40% obesity, the need is massive

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Irregular use may result in suboptimal weight loss, weight regain during gaps, or failure to achieve target weight reduction

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