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By modulating the M1 to M2 phenotype switch, signals such as GLP-1 could indirectly safeguard adipose tissues against inflammation

Large outcome trials LEADER, SUSTAIN-6, REWIND, SELECT, and the more recent SOUL trial, which included 788 Indian patients have shown that certain GLP-1 drugs meaningfully reduce heart attacks, strokes, and cardiovascular death [5][6], with a 26% reduction in heart attacks among Asian participants in SOUL

Results of bariatric surgery in 24 children/adolescents PWS compared to 72 non-PWS subjects matched for age, gender and BMI, undergoing a laparoscopic sleeve gastrectomy, have recently been published [107]
Linagliptin exhibits the highest potency in enzyme inhibition among the DPP4is
Cinnamon is another natural alternative with promising effects

An expert weighs in on why hidden side effects, such as Ozempic chills, may occur
