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Description
Prespecify mechanistic endpoints, include appropriate comparators, and ensure diverse, representative populations

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Nearly 72% of participants with prediabetes achieved normoglycemia by study conclusion, suggesting potential disease-modifying effects beyond symptomatic treatment

remains in clinical trials Mechanism targets three metabolic hormone receptors simultaneously Key data Phase 2 trial (NEJM 2023) reported ~24% average weight loss at 48 weeks at the highest dose Availability not available as an approved prescription peptide GLP3 Weight Loss role education only

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