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10.1002/iub.1182 IUBMB Life 29 LytriviM.Anne-LaureC.PoitoutV.CnopM
Exenatide and lixisenatide are primarily cleared through the kidneys, while liraglutide, dulaglutide, semaglutide, and tirzepatide undergo proteolytic degradation throughout the body with minimal renal excretion of intact drug

When you take a GLP-1 medication, it stimulates insulin release when your blood sugar is high and prevents your liver from making too much glucose (sugar)

Patients typically begin using GLP with a lower dose that is gradually increased over several weeks, which helps minimize the onset of any potential side effects and helps the body to adjust to the medication
