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One you might expect, one you might not expect

What should I eat while on tirzepatide

Increase Soluble and Insoluble Fiber Many patients consume less fiber on GLP-1 medications due to reduced appetite

Notably, in vitro findings involving intestinal absorption of P-gp substrates have been performed using Caco-2 monolayers, although these cells have variable P-gp expression based on the culture conditions (61) and it is indicated that they overexpress P-gp (62)

it doesn't permanently rewire your metabolism once you stop

They can help rule out underlying conditions that may be contributing to the pain, adjust your dose if necessary, or suggest alternative medications if needed