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Knockout of SLC5A2, which encodes the protein of SGLT-2 in rodents, reportedly caused polyuria, hyperphagia, increased glucosuria, and decreased aldosterone, and increased circulation renin

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FIGURE 4 Berberine activated GLP-1/GLP-1R/PKA signaling pathway in Min6 cell Min6 cell is a cell line established in insulinoma obtained by targeted expression in transgenic mice, and retains the physiological characteristics of normal cell

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McBeth, M.D
