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In his book, Metabolical, renowned paediatric endocrinologist Dr

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We previously reported that, among all the naturally occurring amino acids, l-valine is the most powerful luminal stimulator of glucagon-like peptide 1 (GLP-1) release from the upper part of the rat small intestine

Yesterday, the World Health Organization published a guideline in JAMA on the use and indications of #GLP-1 therapies for the management of #obesity in adults

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There's also data suggesting that in some cases, people who take GLP-1s for several years can start to experience a waning effect - perhaps a drug resistance - where they start to regain some weight, even while taking the medication