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Adapted from [96]

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24, 25 Physical activity level was calculated by dividing 24-h EE by sleeping energy expenditure with the lowest radar output

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Based on UK prescribing information for licensed medicines in related drug classes, women planning a pregnancy should discontinue treatment before attempting to conceive

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However, native GLP-1 has a half-life in vivo of circa 2 min, which results from rapid degradation by the dipeptidyl peptidase-4 enzyme

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