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Description
GLP-1-RA such as Ex-4 and Liraglutide modulate multiple signaling pathways in hMSC and progenitor cells to enhance osteogenesis, suppress adipogenesis, promote survival, and reduce inflammation
When HbA 1c was measured in %, tirzepatide at doses of 15 mg, 10 mg and 5 mg demonstrated greater efficacy than semaglutide at doses of 2.0 mg (MD = 0.38% [95% CI 0.75% to 0.01%]), 1.0 mg (MD = 0.45% [95% CI 0.60% to 0.31%]) and 0.5 mg (MD = 0.51% [95% CI 0.68% to 0.33%]), respectively (ESM Table 7)

Keep track of your doses and report to your doctor if you notice any significant adverse effects

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They also slow food digestion by increasing the amount of time it takes for food to pass through the digestive system

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