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Two weeks after DT injections, the body weights of iDTR mice and iDTR:: Pomc -Cre mice were 24.22.2 g ( n =11) and 25.61.4 g ( n =8), respectively
Among the most well-understood behavioral mechanisms of GLP-1 in the brain is its ability to restrict feeding behavior through its targeting of the PVH of the hypothalamus and the central amygdala [50, 54]

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The GLP-1 receptor agonists approved for weight loss include: Zepbound (tirzepatide), Saxenda (liraglutide), and Wegovy (semaglutide)
