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However, definitive evidence from adequately powered human trials demonstrating cognitive benefits is still lacking, and ongoing phase 3 studies are investigating these potential effects

In a study with eight poorly controlled T2DM patients who received a liquid meal via a nasogastric tube and exogenous infusion of GLP-1 to achieve plasma levels of about 70 pM, gastric volume remained constant over 2 hours, and plasma glucose returned to normal fasting values within 3 4 hours (152)

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Fralick, Zinman

3.2.2 Liraglutide LIR was formed by adding a 16-carbon palmitoyl fatty acid to the 26th position of GLP-1 by gene recombination technology and replacing the 34th position of lysine on GLP-1 with arginine

Therefore, both these lifestyle factors and obesity itself represent a significant risk factor for metabolic disease T2DM [3, 5]