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When assessing WL post-bariatric surgery and WR thereafter before initiation of therapy, our analysis found no significant differences between the GLP-1RAs and placebo groups, with (SMD = 0.23, 95% CI 0.36 to 0.81) for WL and SMD = 0.33, 95% CI 0.11 to 0.77) for WR, respectively (Supplementary Figs

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GLP-1 receptor agonists (GLP-1RAs) like semaglutide and tirzepatide are increasingly used in clinical practice, given their proven efficacy in managing obesity and type 2 diabetes (T2D) [1]

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