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Side-by-Side Comparison Common Side Effects What to Expect Both medications share a similar side effect profile, particularly in the early weeks as your body adjusts to the dose

Muscle loss While most weight loss includes some level of muscle loss, research shows that the percentage can be much higher in people taking GLP-1s amounting to 15%40% of their total weight loss

This uncertainty may reflect limitations in statistical power, particularly for MR-Egger, which requires stronger assumptions and larger sample sizes to detect causal effects

Researchers who skip titration steps or escalate doses too quickly experience dramatically worse GI symptoms

After 2-4 weeks of good tolerance, the dose increases to 1-1.5 mg daily

No correlation exists between Mounjaro injection sites and lymph node reactions