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03 Maintain Once-Weekly Use Once the recommended maintenance dose is reached, Celtuide should be taken once weekly on the same day each week

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This is common as the body starts to adapt to the medication, but it usually improves after the first few days

If magnesium citrate is needed regularly for more than one week, consultation with a healthcare professional is advisable

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Figure 2 3.1.1 Cancer-associated fibroblasts (CAFs) TME includes not only immune cells but also stromal cells, and CAFs are the main stromal cell type in the TME