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Without insurance coverage, GLP-1 medications can cost $936 to $1,349 per month, so the Bridge Program represents a significant reduction in out-of-pocket costs

Theyre serious medications with strict usage requirements that are intended for chronic weight management

It is medically dangerous

In STEP 1, the phase 3 trial that led to semaglutide's approval for obesity, participants lost about 15% of their body weight over a year

GLP-1 receptor agonists work by mimicking the incretin hormone glucagon-like peptide-1, which enhances glucose-dependent insulin secretion, suppresses glucagon release, slows gastric emptying, and promotes satiety

To explain the analgesic effects of liraglutide, we hypothesized that its anti-inflammatory properties could play a central role