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It represents a clinically significant manifestation of diabetic autonomic neuropathy and arises from a complex interplay of sustained hyperglycemia, oxidative and nitrosative stress, advanced glycation end-product accumulation, impaired insulin/IGF-1 signaling, lipid dysmetabolism, and inflammatory activation

Originally developed for diabetes and weight management, GLP-1 medications, including semaglutide and tirzepatide, now intersect with the care of patients with inflammatory arthritis, osteoarthritis and systemic []

Well discuss potential therapeutic benefits, side effects + safety considerations related to GLP-1-based therapies

Tirzepatide (Mounjaro, Zepbound) is a...

Diabetes or high blood glucose during pregnancy can lead to defective fetal development, premature delivery, high birth weight, miscarriage, or stillbirth.