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Some researchers have suggested that GLP-1 agonists might have potential neuroprotective effects and could theoretically improve mood in certain contexts, though this is based primarily on preclinical studies and limited human data

Patients on GLP-1 therapy sometimes experience nausea and reduced fluid intake, both of which concentrate uric acid in the kidneys and joints
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Even without PCOS, improving insulin function can help restore ovulation and hormone balance, which may improve fertility
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