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Constipation, fatigue, and gastrointestinal discomfort round out the common complaints

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Both medications are highly effective for weight loss, but there are some key differences: Semaglutide (Ozempic/Wegovy): Primarily acts as a GLP-1 receptor agonist and has been shown to result in around 15-18% weight loss over time for many patients

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It directly asked the question many people care about most: How does tirzepatide perform against semaglutide in the same study

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The other is a fundamental protocol change with significant safety implications

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