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This phenomenon is directly correlated with increased leptin bioavailability in obese individuals, leading to heightened C-reactive protein binding to LEPR at multiple sites, thereby modifying the pleiotropic effects of leptin
On this measure, the averages were 17.6%, 23.7% and 25.0%, compared with 3.9% on placebo
[DOI] [PMC free article] [PubMed] [Google Scholar] 145.Aksoy D, et al
Wegovy 7.2mg is available as single-dose pre-filled pens