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Description
Direct contact of nutrients with intestinal L-cells on the apical intestinal lumen produces an initial secretory peak as early as 1015 min after consumption of a meal, followed by a secondary peak around 3060 min post-consumption [11]

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318:1460-1470 [PMC free article: PMC5817971] [PubMed: 29049653] 379

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Both are clinically legitimate when prescribed by licensed providers
