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Other STEP trials reported similar sustained losses around 15%

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However, Wegovy does not replace a healthy diet or physical activity, but is used as part of a structured treatment plan

Weight loss and lifestyle changes have proven to be effective in restoring menstrual regularity and reproductive function, improving hyperandrogenism, glucose and lipid metabolism, and insulin sensitivity, thus reducing cardiovascular risk in women with PCOS [18,19,20]
None of the grants has any relation to the work presented in the article

This is probably due to the fact that, in order to study these mechanisms, the techniques required are excessively invasive
