side effects.of semaglutide Semaglutide: Double-edged Sword with Risks and Benefits Weighing up the Risks: GI

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The Science of Healthy Aging: How GLP-1 Therapy, Hormone Optimization, and Precision Longevity Medicine Are Transforming Perimenopause and Menopause

June 2, 2026 Results of an American College of Radiology-managed retrospective study involving 110,000 womenpresented at the 2026 ASCO Annual Meeting, shows that those who took GLP-1 medications were up to 35% less likely to develop breast cancer than those who did not take GLP-1 drugs. ACR urges funding of a large prospective study to clarify impact of these drugs on cancer incidence and prevention.

In the largest pharmacogenomics GWAS of GLP-1 medications to date (15,237 participants, replicated in the All of Us cohort), researchers identified a missense variant in GLP1R the gene encoding the very receptor that semaglutide and tirzepatide bind that significantly predicts how much weight a person loses on treatment

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