reduce insulin dose when starting glp-1 receptor agonist Algorithm for titration in T2DM. TDD, total daily dose; GLP-1 Genetics: How Genes Affect
Description
Slower dose escalation
[PMID: 38079178]
153.7 5.4 mmHg at Day 28
Interestingly, female participants lost more weight than male participants over the 48 weeks, achieving 28.5% and 21.9% with 12 mg, respectively
However, hypoglycemia has been reported in up to 9% of overdose cases, even in the absence of insulin or sulfonylurea co-administration, particularly in non-diabetic or lean individuals
Chronic inflammatory responses at the injection site have been reported due to prolonged subcutaneous GLP-1RA use [32]
