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Third, GLP-1 reduces the secretion of proinflammatory cytokines such as interleukin-6, tumor necrosis factor-, and interferon-c9,10,11)
Diminished adiponectin levels result in less effective fatty acid oxidation, causing fat to accumulate in tissues and potentially leading to insulin resistance

Breaking the tablet will disrupt this process, making the medication less effective

Individual genetic predispositions play a role in how efficiently an athlete metabolizes GLP-1 therapy

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