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In SURPASS-4, Mounjaro lowered patient weight by 14 pounds (5 mg), 20 pounds (10 mg), and 23 pounds (15 mg) compared to a gain of 4 pounds with insulin glargine

Polypharmacology refers to the combination of several structurally related hormones into a single entity

When prescribed for weight management, the following drugs will soon be eligible for Part D coverage: Foundayo Wegovy (injection and oral tablet) Zepbound (mimics GLP-1s and another hormone, GIP) Medicare will also cover Wegovy for the risk reduction of major adverse cardiovascular events for those with established heart disease and/or who have obesity or are overweight

Confirm with your own physician whether a compounded GLP-1 medication is appropriate given your full medical history

Visterra/CSLs sibeprenlimab and Vera Therapeutics atacicept are both advancing to bring novel mechanisms to kidney diseases such as in IgA nephropathy (IgAN)

Here are Vocca's tried-and-true ways to make up for potential deficiencies: Vitamin D: "Consume fortified orange juice and dairy foods, mushrooms and fatty fish like salmon