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Description
Mechanism: Early retinopathy worsening is linked primarily to rapid glycaemic improvement rather than direct retinal toxicity of GLP-1RAs

Tirzepatide combines GLP-1 activity with GIP activity, another hormone involved in metabolic regulation, which may help explain why its weight-loss results have outpaced earlier medications in clinical trials
As a highly selective GLP-1 receptor agonist, Semaglutide is designed to mimic the action of endogenous metabolic signaling hormones

I am a Caribbean person and the meals rivaled those of my grandmother

doi:10.1016/j.phrs.2015.02.003 112

[DOI] [PMC free article] [PubMed] [Google Scholar] 91.Drucker D.J., Nauck M.A