semaglutide and shortness of breath GLP-1s Shortness of breath : r/Semaglutide

These findings demonstrated novel biological function of CGA as a GLP-1 secretagogue

gastrointestinal upsets, anaphylaxis, angioedema and drug-interaction as well as long-term ones viz

These drugs significantly reduced rates of #coloncancer (16% fewer cases) and #rectalcancer (28% fewer cases), among others like post-menopausal #breastcancer, #endometrialcancer, and #pancreaticcancer

After reconstitution (mixed with bacteriostatic water)

To improve the health of Americans, in June 2021, the FDA approved semaglutide, a once-weekly injection, for chronic weight management in adults when used in combination with a healthy diet and exercise.

What stood out: CagriSema achieved 23.0% weight loss at 84 weeks (efficacy estimand) Tirzepatide achieved 25.5% On the treatment-regimen estimand, weight loss was 20.2% vs 23.6% Primary endpoint not met: CagriSema did not demonstrate non-inferiority vs tirzepatide on weight loss at 84 weeks Why this matters This is a reminder that in obesity pharmacotherapy, very effective and best-in-class are not the same conversation