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MASH is a severe form of fatty liver disease in which fat buildup, inflammation and tissue scarring can lead to cirrhosis and liver failure

Ongoing studies, including TOGETHER-PsA and TOGETHER AMPLIFY-PsA, are expected to generate critical real-world data on tolerability, metabolicimmune interactions, and long-term safety of this combined therapeutic approach

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As part of the incretin hormones, GLP-1 has three known mechanisms of action: activating glucose-dependent insulin secretions, thereby reducing plasma glucose, suppressing glucagon secretion, and delaying gastric emptying [3]

This resource includes hand-crafted patent highlights featuring synthetically lethal Pol inhibitors from linkedin_mention(urn:li:organization:1603|AstraZeneca) and linkedin_mention(urn:li:organization:1399|GSK) , SARM1 Inhibitors for neurodegenerative indications and our best guess at the identity of linkedin_mention(urn:li:organization:163993|Gilead Sciences) ' small molecule GLP-1R agonist GS-4571 Full article | Drug Hunter's 2023 Patent Review of GLP-1R Agonists June 2024 Patent Highlights: GLP-1R Agonists, Pol Inhibitors, Non-Ab PD-L1 Inhibitors and More