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Theres a big footnote for this trial that takes us back to the Bhaumik award and why there was such a long time before the realization the GLP-1 drugs could be useful for obesitypeople with diabetes on GLP-1 drugs didnt lose much weight
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It is intriguing to note that a proposed function of GLP-1 includes acting as a controller for intestinal lipid absorption, mediated through downregulation of apoB

95% CI 7.24, 3.87)

Governments looking to reduce the costs of healthcare and boost economic productivity also need to tread carefully when encouraging the use of GLP-1 drugs in people with obesity without addressing the wider socio-economic challenges patients face as well as the problems posed by the rise in ultra-processed food and poor provision of physical exercise facilities

In patients with T2DM, the reduction in HbA1c is not overtly different between twice daily or once daily administration of lixisenatide [892]