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A prospective study found (189) that 1 year after bariatric surgery, NASH was eliminated in 85% of patients, indicating that weight loss was closely related to the histological improvement of fatty liver

On the other hand, FDA-approved medications like Wegovy and Zepbound offer a proven path to weight loss with significantly lower risks

[DOI] [PubMed] [Google Scholar] 142.Flock G., Cao X., Drucker D.J

When these receptors are stimulated, they activate pathways involved in cell growth, repair, and defense against damage

However, around the time that bariatric surgerys positive effects on diabetes and cardiovascular outcomes were emerging from observational studies, researchers were taking note of the weight-loss and cardiovascular effects of the GLP-1 receptor agonist medications (GLP-1 RAs) used to treat type 2 diabetes

GLP-1 receptor agonists lower HbA1c by 11.5% but this may be dependent of the type of GLP-1 receptor agonist prescribed, the dosage, baseline HbA1c levels and glucose-lowering co-medication [24]