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Genes Dev (2005) 19(8):87790.10.1101/gad.1295405 183 HolstJJ
Semaglutide activates the GLP-1 (glucagon-like peptide-1) receptor, for example
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Depressed patients are often characterized by elevated blood cortisol levels and changes in the circadian secretion of this hormone, an increased number of corticotropin-releasing hormone (CRH)-expressing neurons in the hypothalamic paraventricular nucleus (PVN), as well as an impairment in a negative feedback mechanism, which can be measured in the dexamethasone suppression test [70, 71]
CMAJ 2021;193:E1836e41
