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Created from PDB ID:1JRJ

Mattioli Introduction GLP-1 agonists like liraglutide have become a powerful tool for weight management, but they often come with digestive side effects and concerns about long-term use

Patients across the country are now coming forward, alleging that the drug caused a serious gastrointestinal condition known as gastroparesis, among other complications like ileus, bowel obstruction, and NAION

Designed to support appetite control and digestion

Diabetesmellitus (DM) is a group of metabolic diseases classified by chronic hyperglycemia resulting from defects in insulin secretion, insulin action, or both

Our functional and structural data suggest that receptor conformational dynamics associated with flexibility of the peptide N-terminal activation domain may be a key determinant of agonist efficacy