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Genetic Predictors of GLP1 Receptor Agonist Weight Loss and Side Effects. Nature , Apr

This signaling involves complex interactions with the brains reward pathways, which are also implicated in addiction and impulse control

NICE recommends these agents particularly for patients with established cardiovascular disease, heart failure, or chronic kidney disease

Assess for clinical improvement

Dont forget to evaluate for lifestyle factors and medical causes (diabetes, alcohol abuse, hypothyroidism, pregnancy) and to review the medication list (pay attention to thiazides, non-selective beta blockers, antipsychotics and others)

Dehydration and vomiting can sometimes stress the kidneys