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However, semaglutide (and dual agonists) appear to have a greater treatment effect on steatohepatitis than resmetirom in MASH and offer unique cardiorenal benefits while not adding to the treatment cost if prescribed for any of the current semaglutide FDA-approved indications: treatment of obesity or overweight with at least one weight-related comorbid condition

Higher doses also amplify semaglutide's effects on nutrient absorption and energy expenditure at the cellular level

If youre considering knee or hip replacement, tell your anaesthetist and orthopaedic team that youre on Wegovy, so they can plan around the medications effect on gastric emptying

The dose was reduced from 1.0 to 0.5 mg in 12.5% of patients, primarily because of gastrointestinal disorders

As a once-weekly treatment, it provides both convenience and effectiveness, making it a promising choice for patients and healthcare providers alike

Bottom Line Phentermine aids short-term weight loss in obesity (BMI 30 or 27 with risk factors like hypertension, diabetes, high cholesterol)