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The signal is widely reported but thinly studied

Mechanisms of GLP-1 Receptor Agonist-Induced Weight Loss: A Review of Central and Peripheral Pathways in Appetite and Energy Regulation (May 17, 2025) Semaglutide (February 11, 2024) Wegovy (Semaglutide) Injection, For Subcutaneous Use

No futility or interim analyses are planned

GLP-1 drugs mimic the effects of this hormone

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Those who have reported a change in sex drive appear to be a small percentage of people taking the medication