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The changes we observed might have been underestimated

This helps you feel fuller, reduces cravings, and improves your body's response to glucose, leading to weight loss

The primary objective of STEP 4 was to compare the effect of a semaglutide SC 2.4 mg injection once weekly versus placebo as an adjunct to a reduced-calorie diet and increased physical activity in patients with overweight or obesity who have reached the target dosage of semaglutide during the run-in period on body weight

the drugs mode of action is relatively simple but limited

Another concern with taking weight-loss drugs is overdosing

Instead, the results suggest that some DM2 DMTs act through indirect, metabolic, or context-dependent mechanisms rather than direct neuroprotection