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Dose-dependent effects of the once-daily GLP-1 receptor agonist lixisenatide in patients with Type 2 diabetes inadequately controlled with metformin: a randomized, double-blind, placebo-controlled trial

Both medications work by mimicking a natural hormone in the body, but they differ in dosages and approved uses

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Semaglutide typically moves from 0.25mg to 0.5mg at week five, then to 1.0mg at week nine

Although weight-loss specific drugs are now licensed, supply is limited, and as a consequence, off-label prescribing of diabetic drugs has continued to grow (particularly of Ozempic (active ingredient: semaglutide) and Mounjaro (active ingredient: tirzepatide))

Oral tirzepatide is in development