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Reduced energy substrate combined with rapid weight loss may deplete glycogen stores and shift metabolic rate downward, contributing to perceived tiredness

How GLP-1 Medications Support Immune Function During Illness Semaglutide works on glucagon-like peptide-1 receptors throughout your body, including immune cells called dendritic cells and T-lymphocytes

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Nausea, mild stomach upset, and reduced appetite are the most frequently reported effects during the first 24 weeks, typically resolving as your body adjusts

Special breathing exercises may provide some relief

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