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Mean percent change in bodyweight Tirzepatide 10 and 15 mg doses were associated with significantly greater reductions in mean percent change in bodyweight at week 72 compared with semaglutide 2.4 mg at week 68 (Figure 2A)

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DRUG INTERACTIONS As with other medications, zonisamide can interact with certain medications, including carbonic anhydrase inhibitors (such as acetazolamide), orlistat (if using zonisamide for a seizure disorder), phenobarbital, primidone, rifamycins, glucocorticoids, and St