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Early exploratory analyses suggest that 3040% of participants in some trials may achieve formal diabetes remission criteria (near-normal HbA1c without additional glucose-lowering therapy), although these figures need to be confirmed in larger phase 3 populations

This might include switching to another GLP-1 receptor agonist, adding or adjusting other oral hypoglycaemic agents, or considering injectable therapies such as insulin if appropriate, in line with NICE guidance (NG28)

Remove the cap from the needle

Different patients want different things

Centrally, GLP-1 receptor activation in the hypothalamus and brainstem suppresses appetite and reduces food intake

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