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Rybelsus acts systemically by mimicking endogenous GLP-1, enhancing glucose-dependent insulin secretion, suppressing glucagon release, and slowing gastric emptying

doi: 10.1172/jci.insight.133429 [DOI] [PMC free article] [PubMed] [Google Scholar] 74.Chen J, Williams S, Ho S, et al

Weight loss injections, such as those containing GLP-1/GIP agonists like tirzepatide, work by mimicking the GLP-1 and GIP hormones, which helps regulate appetite and blood sugar levels

A small study of MINOCA patients found that 25% had low myocardial perfusion reserve, suggesting potential involvement, but further research is needed to establish its role as a cause of MINOCA

The type 2 diabetes formulations of these medications also have high price tags, though they are significantly lower

This occurs because the medications effects on appetite suppression and metabolic control diminish once treatment is discontinued