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Dungan & DeSantis, 2026)
Retatrutide Phase 3 results look promising, but the drug is not FDA-approved for public use
& Tan, T
Although GLP-1R expression is relatively low in many peripheral organs, GLP-1 medicines exert distinct antiinflammatory effects through both direct and indirect mechanisms that involve immune, vascular, and neural crosstalk (Figure 4)
These specialized immune cells express GLP-1 receptors and when GLP-1(whether from native production or GLP-1 agonists) activates these IELs via GLP-1R it helps to suppress localized T-cell induced inflammation
J Diabetes Res 2021
