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Hawkins, J., Cifuentes, M., Pleshko, N
2014;9(5) doi: 10.1371/journal.pone.0097554.e97554 [DOI] [PMC free article] [PubMed] [Google Scholar] 61.Hattori Y., Jojima T., Tomizawa A., et al

That decline maps almost exactly to the slow metabolic decay people complain about in their 40s and 50s

Food cravings Calories In Weight Gain Treat the Food Cravings

However, given the novelty of this therapeutic approach, the available evidence may be influenced by publication bias and early optimism, and long-term mechanistic and clinical outcome data remain limited

Lancet 406 , 149162 (2025)
