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20,21,23 Nauck et al found that 35%44% of patients treated with GLP-1RA complained of one or more adverse gastrointestinal effects including nausea, vomiting, and diarrhea

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Providers can also screen and manage related chronic conditions such as type 2 diabetes, high cholesterol and hypertension, helping close additional care gaps during treatment

These developments may contribute to future claims alleging inadequate warnings, insufficient dosing instructions, or failure to address foreseeable risks tied to widespread consumer use

Extended release: CSF turnover (~6 hours) allows sustained exposure at synaptic nodes