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In general, the longer-acting GLP-1 agonists which are injected weekly, such as semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro), are associated with greater weight loss than the shorter-acting GLP-1 agonists such as liraglutide (Saxenda)

Formulation: Does it contain the desired ingredients in sufficient quantities, and have they been sourced appropriately

These medications can lead to muscle loss along with fat loss

Narula said people currently taking compound versions of GLP-1 medications should reach out now to their health care provider to ask for a prescription for the branded version of the medication

Patients should avoid choosing a medication based only on headline weight-loss percentages

After 4 weeks, the dose should be increased to 5 mg