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The SELECT trial specifically demonstrated that semaglutide reduces major adverse cardiovascular events by 20% in patients with established cardiovascular disease, regardless of diabetes status

Dissociable Hindbrain GLP1R Circuits for Satiety and Aversion

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Rosenstock J, Vico M, Wei L, Salsali A, List JF

84 Interestingly, T2DM and IR are found to have a toxic effect on ovaries, leading to the degeneration of the gonadal tissue and the reduction in the ovarian reserve
