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Description
Retatrutide carries the same class-level concern
A systematic review of 26 studies including 3020 participants showed mixed and inconclusive effects of GLP-1 RAs on psychiatric symptoms
10.1007/s11064-017-2250-8 31 ColinI
This central GIPR activity is one reason tirzepatide reduces cravings and alters food preferences in ways patients frequently describe as different from their experience with GLP-1-only agents
There is no primary-source efficacy data supporting those human doses
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