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Albiglutide demonstrated the highest risk (0.156%), while tirzepatide showed the lowest (0.022%)

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For a full breakdown of potential risks, see the Wegovy safety information and Ozempic safety information

However, total body GLP-1R knockout (KO) mice maintain brown fat thermogenesis [114], indicating the presence of a sub-population of neurons regulating energy expenditure, and further research should focus on those extraordinary serotonergic neurons involved in appetite and thermogenesis

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