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3033 However, the application of SGLT-2i in some studies has been reported to significantly increase total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), non-high density lipoprotein cholesterol (non-HDL-C), and high-density lipoprotein cholesterol (HDL-C) and decrease triglyceride (TG)

That is a meaningful clinical outcome beyond just weight loss

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Additional Insights: Risk factors for both include hypertension, diabetes, smoking, high cholesterol, obesity, and family history

If the solution is not clear, it may be a sign of contamination or degradation, and we recommend not using it

doi: 10.1001/archinte.166.6.689