getting pregnant while taking semaglutide Can the new diabetes and weight loss drugs affect reproductive health? — Those Nerdy Girls Semaglutide and Pregnancy: Safety Guide

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After menopause, estrogen deficiency leads to an increase in osteoclast recruitment and a decrease in osteoclast apoptosis

Many GLP-1s are FDA approved for more than just weight loss, including type 2 diabetes, cardiovascular risk reduction, and even stroke prevention in certain populations, says Supriya Rao, MD, an obesity physician and the director of medical weight loss at Lowell General Hospital in Lowell, Massachusetts

In between-drug comparisons, tirzepatide 15 mg and 10 mg outperformed semaglutide 1.0 mg and 0.5 mg and tirzepatide 5 mg was superior to semaglutide 0.5 mg, while no differences were found between semaglutide 2.0 mg and any of the tirzepatide doses (ESM Table 9)

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Dietary changes: GLP-1s help you feel fuller for longer, which can make you eat less food and therefore less fiber